3D printing Report

The 3D printing of medical devices and living tissues is forecast to exceed $8.1bn by 2029

3D Printing in the Medical and Dental Industry 2019 - 2029

Trends, opportunities, and outlook

By Dr Bryony Core and

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From its humble beginnings in the late 1980s, through to the global force that it is today, the capabilities of 3D printing technology have expanded dramatically, to establish itself as an attractive manufacturing solution for prototyping and production. Conferring advantages such as shorter lead times, reduced waste and opportunity for mass customisation, the potential of 3D printing was quickly realised and has gone from strength to strength since. One of the key industries to have successfully leveraged these advantages is the medical and dental industry. 3D printing allows the production of a wide range of devices such as hearing aids to Invisalign® aligners to prosthetic limbs which are tailored to meet the specific needs of the patient while adhering to a narrow regulatory framework. The range of applications is not limited to medical devices or prosthetics: as the development of 3D bioprinting continues to evolve, there is scope for the implantation of living tissues as part of regenerative medicine. Key players are now capitalising on this potential, and the size of the opportunity presented by 3D printing in the medical industry will exceed $8.1 billion by 2029. This rapid growth is analysed, and implications evaluated in the latest market intelligence report from IDTechEx Technology Analysts Dr Bryony Core and Dr Nadia Tsao: 3D Printing in the Medical and Dental Industry 2019 - 2029: Trends, Opportunities and Outlook.
 
Technology, applications and case studies
In 2018, the range of applications of 3D printing and 3D bioprinting within the medical and dental industry is tremendously diverse. An overview of the latest printing processes and key materials utilised within the medical industry is provided, before investigating in detail the most commonly encountered printers and materials utilised in each speciality. This report takes an in-depth look into the most prolific applications, providing detailed case studies of leading edge companies developing innovative products leveraging this technology. Furthermore, this report provides an overview of regulatory challenges faced in bringing 3D printed products to market, discussing the current regulatory outlook as well as outstanding barriers that must be addressed.
 
Market outlook
This report provides an overview of the revenues generated from the sale of 3D bioprinting and 3D printing equipment, materials and software to the medical industry as well as a comprehensive insight into the drivers and restraints affecting technology development for all key application areas. This report provides case studies and SWOT analyses for the most prolific disrupters developing 3D printed medical devices and living tissues, as well as analysing the medical 3D printing supply chain including printer manufacturers and materials formulators. IDTechEx conducted exhaustive primary research with companies across a range of industries developing equipment for medical applications of 3D printing for key insights into the drivers and restraints affecting the growth of this technology.
 
Key questions that are answered in this report
  • Who are the key players developing equipment and materials for medical applications of 3D printing?
  • What are the strengths and weaknesses of different 3D printing technologies?
  • What are the potential medical applications of each type of 3D printing technology?
  • How has 3D printing already been used to create medical devices?
  • Which types of printers and materials are used according to medical specialities?
  • Which printers support materials that can be used for medical devices?
  • What are the unmet needs of technicians and practitioners that are not satisfied by current technology?
  • What are the market shares of those active in the market?
  • What are the key drivers and restraints of market growth?
  • How will revenues from sales of hardware, materials and software grow from 2019 to 2029?
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Table of Contents
1.EXECUTIVE SUMMARY
1.1.The seven different types of 3D printing processes
1.2.3D printing in healthcare: regulatory perspectives
1.3.3D printing as a surgical tool
1.4.Why use models to improve patient care, standards and efficiency
1.5.3D printing custom plates, implants, valves and stents
1.6.Adoption outlook of orthopaedic implants from 2019 to 2029
1.7.Digital dentistry and 3D printing
1.8.The digital dentistry workflow
1.9.Other medical devices
1.10.3D printing pharmaceuticals
1.11.What Can Tissue Engineering Do?
1.12.3D Bioprinting Process
1.13.3D Scaffold: Requirements
1.14.3D printing is poised for widespread adoption
1.15.Overall 3D Bioprinting Market Forecast 2019 - 2029
1.16.Annual revenue from 3D printing for medical devices
1.17.Annual revenue from medical and dental 3D printing
2.INTRODUCTION
2.1.Glossary: common acronyms for reference
2.2.The seven different types of 3D printing processes
2.3.Major material-process relationships
2.4.Why adopt 3D printing?
2.5.In-house or outsource?
2.6.3D printing in healthcare: regulatory perspectives
3.3D PRINTING TECHNOLOGIES: HARDWARE
3.1.Extrusion: Thermoplastics (TPE)
3.2.Vat photopolymerisation: Stereolithography (SLA)
3.3.Vat photopolymerisation: Digital Light Processing (DLP)
3.4.Material jetting
3.5.Powder bed fusion: Selective Laser Sintering (SLS)
3.6.Powder bed fusion: Direct Metal Laser Sintering (DMLS)
3.7.Powder bed fusion: Electron Beam Melting (EBM)
4.3D BIOPRINTING TECHNOLOGIES
4.1.3D Bioprinting: Inkjet
4.2.3D Bioprinting: Extrusion
4.3.3D Bioprinting: Laser-Induced Forward Transfer
4.4.3D Bioprinting: Microvalve
5.3D PRINTING TECHNOLOGIES: SOFTWARE
5.1.Overview of 3D printing software segments
5.2.Relationship between 3D printing hardware and software
5.3.Computer Aided Design (CAD)
5.4.Computer Aided Engineering (CAE): Topology
5.5.Computer Aided Manufacture (CAM): Build preparation
5.6..STL files
5.7.Converting DICOM scans to a 3D printed device
6.APPLICATIONS
6.1.Applications: Surgical tools, guides and models
6.1.1.3D printing as a surgical tool
6.1.2.Motivation for adoption
6.1.3.Why use models to improve patient care, standards and efficiency
6.1.4.3D printing for surgical application and radiography
6.1.5..STL libraries of anatomical models
6.1.6.3D printing as a surgical planning and determination tool
6.1.7.3D printing processes and materials for surgical applications
6.1.8.Photosensitive resins
6.1.9.Photosensitive resins
6.1.10.Pathfinder ACL guide
6.1.11.Cost effective and agile preprocedural surgical models
6.1.12.Case study: pre-procedural simulation for brain aneurysm
6.1.13.Regulatory overview
6.2.Applications: Implantable devices
6.2.1.3D printing custom plates, implants, valves and stents
6.2.2.Motivation for adoption
6.2.3.Titanium alloy powders
6.2.4.Titanium alloy powders
6.2.5.High temperature thermoplastic filaments and powders
6.2.6.High temperature thermoplastic filaments and powders
6.2.7.PMI Polymers and Filaments for scaffolds and stents
6.2.8.Case study: hip replacement revision surgery
6.2.9.Case study: canine cranial plate in titanium
6.2.10.Regulatory overview
6.2.11.Adoption outlook of orthopaedic implants from 2019 to 2029
6.3.Applications: Dental tools, models and prosthetics
6.3.1.Digital dentistry and 3D printing
6.3.2.Motivation for adoption
6.3.3.The digital dentistry workflow
6.3.4.3D printing processes and materials for dental applications
6.3.5.Key 3D printer providers
6.3.6.Photosensitive resins
6.3.7.Photosensitive resins
6.3.8.Key dental photosensitive resin developers
6.3.9.Metal powders
6.3.10.Metal powders
6.3.11.Case study: The Invisalign Story
6.3.12.Case study: mandibular reconstructive surgery
6.3.13.Case study: "Orthoprint, or How I Open-Sourced My Face"
6.3.14.Company profile: Digital Smile Design
6.3.15.Regulatory overview
6.4.Applications: Orthoses, prostheses and other medical devices
6.4.1.Other medical devices
6.4.2.Motivations for adoption
6.4.3.Applications: hearing aids
6.4.4.Applications: orthotic braces
6.4.5.Applications: orthotic insoles
6.4.6.Applications: prosthetics
6.4.7.Dad designs son's 3D printed prosthetic arm
6.4.8.Applications: eyewear
6.4.9.Applications: wheelchair
6.4.10.Applications: respiration masks
6.5.Applications:Pharmaceuticals
6.5.1.3D printing pharmaceuticals
6.5.2.Motivations for adoption
6.5.3.Material/Method Overview - Jetting
6.5.4.Jetting - Advantages and Disadvantages
6.5.5.Material/Method Overview - Thermoplastic
6.5.6.Thermoplastic - Advantages and Disadvantages
6.5.7.Applications: Novel Dissolution Profiles
6.5.8.Novel Pill Architectures
6.5.9.Applications: Personalized Medication
6.5.10.Applications: Novel Drugs and Drug Testing
6.5.11.Key players
6.5.12.Aprecia Pharmaceuticals
6.5.13.Regulatory overview
6.6.Applications:Living tissues
6.6.1.What Can Tissue Engineering Do?
6.6.2.Motivations for adoption
6.6.3.3D Bioprinting Process
6.6.4.3D Scaffold: Requirements
6.6.5.3D Scaffold: Process
6.6.6.Material Overview - Hydrogel
6.6.7.Hydrogel - Advantages and Disadvantages
6.6.8.Material Overview - Polymer Scaffold
6.6.9.Polymer Scaffold - Advantages and Disadvantages
6.6.10.Applications: Product Testing
6.6.11.Applications: Drug Screening
6.6.12.Applications: Personalized Medicine
6.6.13.Applications: Cell-Based Biosensors
6.6.14.Applications: Food and Animal Products
6.6.15.Applications: Aesthetics
6.6.16.Case Study: Aesthetics
6.6.17.Applications: Regenerative Medicine
6.6.18.Case Study: Regenerative Medicine
6.6.19.Regulatory - In Vivo Applications
6.6.20.Key Players
6.6.21.3D Bioprinting Players
6.6.22.Relevant IDTechEx Research
7.REGULATORY PERSPECTIVES
7.1.Medical Grade Materials
7.2.Medical Grade Materials
7.3.Medical Device Pathways
7.4.FDA Medical Device Classifications
7.5.FDA Medical Device Timelines
7.6.FDA Drug and Biologics Pathways
8.MARKET ANALYSIS AND FORECAST
8.1.3D bioprinting: Market barriers
8.2.Growing 3D Bioprinting Market
8.3.Overall 3D Bioprinting Market Forecast 2019 - 2029
8.4.The state of the market for 3D printed medical devices
8.5.Annual revenue from 3D printing for medical devices
8.6.Annual revenue from medical and dental 3D printing
9.CONCLUSIONS
9.1.Outlook: Surgical tools, guides and models
9.2.Outlook: Implants
9.3.Outlook: Dental appliances, models and tools
9.4.Outlook: Other medical devices
9.5.Outlook: 3D printed pharmaceuticals
9.6.Outlook: 3D living tissues
9.7.3D printing is poised for widespread adoption
9.8.3D Printing Research
10.COMPANY PROFILES
10.1.3D Bioprinting Solutions/ Vivax Bio
10.2.3D Biotek
10.3.3D Ceram
10.4.3D Systems
10.5.3Dynamic Systems (3DS)
10.6.Aether
10.7.Allevi
10.8.Arcam AB
10.9.Aspect Biosystems
10.10.BellaSeno
10.11.BioDan Group
10.12.BIOLIFE4D
10.13.Carbon3D
10.14.Cellbricks
10.15.Cellenion
10.16.Cellink
10.17.Cyfuse Biomedical
10.18.Cytosurge
10.19.Digilab
10.20.DiHeSys - Digital Health System
10.21.EOS GmbH
10.22.Formlabs
10.23.GeSiM
10.24.Materialise
10.25.Microdrop Technologies
10.26.MicroFab Technologies
10.27.Oxford Performance Materials
10.28.Peptigeldesign
10.29.Photocentric
10.30.Poietis
10.31.Prellis Biologics
10.32.Regemat 3D
10.33.RegenHU
10.34.Ricoh
10.35.SE3D
10.36.Sichuan Revotek
10.37.Stratasys
10.38.SunP Biotech International
 

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