Electric powertrain is indispensable for autonomous vehicles as it offers a) higher fuel efficiency and reduced CO2 emissions, b) an easier platform to support drive-by-wire systems needed for vehicle autonomy, and c) as battery prices keep dropping sharply, an attractive proposition of lower cost of ownership and maintenance, especially for fleet owners in ride-sharing ecosystem. However, the integration of vehicle autonomy with electrification is not going to be simple additive manufacturing. For instance, in a level 5 autonomous car, autonomous functionality-enabling electronics power demand can be 400W or more that when fed by the main battery can reduce electric drive significantly (up to 15%, especially in city drive, depending on the battery and e-powertrain design). However, other factors such as smoother driving profile of a connected autonomous vehicle compared to human driving can help enhance electric drive range, especially as the market penetration of autonomous vehicles increase. These factors not only impact electric drive range but also have significant implication for battery, inverter and motor reliability. This talk will highlight these critical implications for electric powertrain that come specifically with vehicle autonomy and talk about the need for co-dependent design for autonomous functionality-enabling electronics and vehicle's electric powertrain.