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| 1. | EXECUTIVE SUMMARY |
| 1.1. | Bioelectronic Medicine |
| 1.2. | Major Forms of Bioelectronic Medicine |
| 1.3. | The Nervous System |
| 1.4. | Bioelectronic Medicine Market Forecast 2019 - 2029 |
| 1.5. | Bioelectronic Medicine Market Breakdown 2019 vs 2029 |
| 1.6. | Cardiac Rhythm Management and Heart Failure |
| 1.7. | Cardiac Market Forecast 2019 - 2029 |
| 1.8. | Cochlear and Retinal Implant Market Forecast 2019 - 2029 |
| 1.9. | Electrical Neuromodulation of the Central Nervous System |
| 1.10. | CNS Market Forecast 2019 - 2029 |
| 1.11. | Pharmaceuticals vs Electroceuticals |
| 1.12. | The Reach of Peripheral Nerve Stimulation is Vast |
| 1.13. | Electrical Neuromodulation of the Peripheral Nervous System |
| 1.14. | Moving to First Line Therapy |
| 1.15. | Next Generation Devices |
| 2. | INTRODUCTION |
| 2.1. | Bioelectronic Medicine: Definition and Scope of Report |
| 2.2. | Major Forms of Bioelectronic Medicine |
| 2.3. | Initiation, Emergence, and Trends |
| 2.4. | The Evolution of Bioelectronic Medicine |
| 2.5. | Rise of Bioelectronic Medicine |
| 2.6. | Pharmaceuticals vs Electroceuticals |
| 2.7. | Bioelectronic Medicine as an Alternative to Opioids |
| 2.8. | The Nervous System |
| 2.9. | How Neurons Normally Function |
| 2.10. | How Neurons Normally Function - The Synaptic Cleft |
| 2.11. | Neuromodulation |
| 2.12. | Neuroprosthetics Defined |
| 2.13. | Re-Engineering Sight and Sound |
| 2.14. | Bioelectronic Device Components |
| 2.15. | Pulse Generators |
| 2.16. | Leads and Electrodes |
| 2.17. | Controllers and Chargers |
| 2.18. | MR Conditional |
| 2.19. | Rechargeable vs Recharge-Free vs No Batteries |
| 2.20. | Applications of Bioelectronic Medicine |
| 2.21. | Challenges to Next Generation Bioelectronic Medicine |
| 3. | MARKET TRENDS |
| 3.1. | Key Market Trends |
| 3.2. | Key Players: Established Applications |
| 3.3. | Abbott Acquires St Jude Medical |
| 3.4. | Key Players: Emerging Applications |
| 3.5. | GlaxoSmithKline |
| 3.6. | Galvani Bioelectronics |
| 3.7. | SetPoint Medical |
| 3.8. | Research Initiatives Drive Basic and Translational Research |
| 3.9. | The BRAIN Initiative |
| 3.10. | Stimulating Peripheral Activity to Relieve Conditions |
| 3.11. | ElectRx |
| 3.12. | Ageing Populations |
| 3.13. | The Impact of Sensory Loss |
| 3.14. | The Prevalence and Expected Rise of Macular Degeneration |
| 3.15. | Back Pain is a Major Cause of Disability |
| 3.16. | Challenges from Bench to Bedside |
| 3.17. | Regulatory: Invasiveness of the Device |
| 3.18. | Regulatory: CE Mark |
| 3.19. | New Regulations in the EU |
| 3.20. | Regulatory: FDA |
| 3.21. | Regulatory: FDA Timeline |
| 3.22. | Reimbursement |
| 3.23. | Moving to First Line Therapy |
| 4. | MARKET FORECAST |
| 4.1. | Introduction |
| 4.2. | Bioelectronic Medicine Market Forecast 2019 - 2029 |
| 4.3. | Bioelectronic Medicine Market Breakdown 2019 vs 2029 |
| 4.4. | Cardiac Market Forecast 2019 - 2029 |
| 4.5. | Cochlear and Retinal Implant Market Forecast 2019 - 2029 |
| 4.6. | Cochlear and Retinal Implant Market Breakdown 2019 vs 2029 |
| 4.7. | CNS Market Forecast 2019 - 2029 |
| 4.8. | PNS Market Forecast 2019 - 2029 |
| 4.9. | PNS Market Forecast 2019 - 2029: Discussion |
| 4.10. | Ongoing Clinical Trials |
| 5. | APPLICATIONS |
| 5.1. | Cardiac Rhythm Management and Heart Failure |
| 5.1.1. | Introduction |
| 5.1.2. | Key Players |
| 5.1.3. | Cardiac Market 2013 - 2018 |
| 5.1.4. | Devices and Indications |
| 5.1.5. | Components |
| 5.1.6. | Implantation Procedure |
| 5.1.7. | Bradycardia and Heart Block |
| 5.1.8. | Pacemakers |
| 5.1.9. | Leadless Pacemaker |
| 5.1.10. | Heart Failure |
| 5.1.11. | Cardiac Resynchronization Therapy |
| 5.1.12. | Implantable Cardioverter Defibrillators |
| 5.1.13. | Extravascular Cardioverter Defibrillator |
| 5.1.14. | Key Trends - Cardiac |
| 5.1.15. | Drivers and Constraints - Cardiac |
| 5.2. | Cochlear Implants |
| 5.2.1. | How We Hear Normally |
| 5.2.2. | Major Technological Developments in Cochlear Implants |
| 5.2.3. | Cochlear Implants |
| 5.2.4. | Outline of a Cochlear Implant |
| 5.2.5. | Special Considerations for Cochlear Implants |
| 5.2.6. | Major Players for Hearing Restoration |
| 5.2.7. | Cochlear |
| 5.2.8. | Advanced Bionics |
| 5.2.9. | MED-EL |
| 5.2.10. | Outlook - Cochlear Implants |
| 5.3. | Retinal Implants |
| 5.3.1. | How We See Normally |
| 5.3.2. | How We See with Retinal Degeneration |
| 5.3.3. | A Brief History of Vision Restoration |
| 5.3.4. | Artificial Retinas |
| 5.3.5. | Artificial Retinas - Epiretinal Implants |
| 5.3.6. | Artificial Retinas - Subretinal Implants |
| 5.3.7. | Intracortical Visual Prosthetics |
| 5.3.8. | Special Considerations for Vision |
| 5.3.9. | Major Players for Neuroprosthetic Sight Restoration |
| 5.3.10. | Second Sight Medical |
| 5.3.11. | Pixium Vision |
| 5.3.12. | Retina Implant |
| 5.3.13. | Outlook - Retinal Implants |
| 5.4. | Central Nervous System |
| 5.4.1. | Introduction |
| 5.4.2. | CNS Players |
| 5.4.3. | CNS Market 2013 - 2018 |
| 5.4.4. | Spinal Cord and Dorsal Root Ganglion Stimulation |
| 5.4.5. | Deep Brain Stimulation |
| 5.5. | Peripheral Nervous System |
| 5.5.1. | Introduction |
| 5.5.2. | Players |
| 5.5.3. | PNS Market 2013 - 2018 |
| 5.5.4. | Vagus Nerve Stimulation |
| 5.5.5. | Trigeminal Nerve Stimulation |
| 5.5.6. | Sacral Nerve Stimulation |
| 5.5.7. | Other Nerve Targets |
| 5.5.8. | Peripheral Nerve Stimulation for Chronic Pain |
| 6. | NEXT GENERATION DEVICES |
| 6.1. | Introduction |
| 6.2. | An Interdisciplinary Approach is Required |
| 6.3. | Visceral Nerve Atlas |
| 6.4. | Neural Interfacing Technology |
| 6.5. | Closed Loop Systems |
| 6.6. | Closed Loop Systems: Requirements |
| 6.7. | Outlook - Next Generation Devices |
| 7. | ACRONYMS |
| 7.1. | List of Acronyms |
| 8. | COMPANY PROFILES |
| Slides | 297 |
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