Dr Giorgio C Mutinati, Scientist-Molecular Diagnostics
AIT Austrian Institute of Technology
The decentralization of the health care system, driven by the demographic change, creates a strong demand for sustainable high volume and low cost biosensors that enable molecular diagnostics outside of laboratories. At present, non-invasive point-of-care rapid tests are mostly available in the form of single-use test strips using color indicators. The reading of these test strips is strongly influenced by subjective visual perception and the results are, therefore, hardly reproducible and only qualitative. To overcome these limitations, we aim to realise an electrochemical single-use sensor, which i) is based on recycling paper as substrate to enable environment-friendly production and disposal, ii) detects quantitatively glucose and ketone bodies in urine to permit the diagnosis of ketoacidosis, iii) is able to contactless communicate the measured values. For this purpose, suitable fabrication processes are developed and their integration is studied. In particular, screen printing for the electrodes on paper, inkjet printing for the biofunctionalisation and a bare-die chip placement process are used. We present our progress towards the full integration of such a system showing its capabilities in detecting glucose, in performing the electrochemical measurements using a highly integrated electronic read-out chip and in transferring contactless the data. This preliminary results indicate the feasibility of recycled paper based biosensing systems with contactless readout sensitive to detect glucose.
Speaker Biography (Giorgio C Mutinati)
Giorgio C. MUTINATI, PhD, after his degree in physics, specialized in micro- and nanotechnology and solid state electronics. After seven years at the R&D departments of semiconductor industries, he joined AIT in 2010 as permanent staff scientist and project manager. Here he established the research activities on printing technologies for the realisation of electrochemical biosensors.
Company Profile (AIT Austrian Institute of Technology)
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The AIT Austrian Institute of Technology is Austria's largest non-university research institute, which acts as bridge between university and industry. The business unit Molecular Diagnostics (www.ait.ac.at/MD) of the Center for Health & Bioresources comprises an interdisciplinary team of about 50 scientists. Within the unit, the Diagnostic Biosensor group combines printing technology and thin film processes with innovative concepts from nano- and bio-sciences. By heterogeneously integrating multi-functional components based on different technologies and materials, novel devices for medical diagnostic applications are developed with a strong focus on point-of-care testing.