Graphene Based Electrochemical Biosensor For Lab On Chip With Rapid Biomarker Detection (Healthcare Sensor Innovations 2019)

Dr Zari Tehrani, Research Fellow Ser Cymru
Swansea University
United Kingdom

Speaker Biography (Zari Tehrani)

Dr Zari Tehrani holds BSc,MSc,MBL,Mres, PhD in Nanotechnology and MRSC. She was awarded as a research Fellow Sêr Cymru II. She was working as a post-doctorate researcher at Swansea University since 2011. Her PhD was on the Functionalisation of Semiconductor Surfaces for Biosensor Applications. In 2013 she joined the WCPC, where she has established herself as an autonomous researcher - developing graphene technologies for a number of new applications. In the context of printing she developed new skills in printing technology and fabrication of functional devices. This was demonstrated successfully by the fabrication of one of the first all-printed rechargeable thin film batteries 1. She had experience on working on Bio-compatible Cellulose nanostructures for advanced wound healing applications by printing techniques 2. She has a unique set of talents, in that she has scientific expertise in biosciences and printing. She is an outstanding researcher within SU's College of Engineering, who has made significant contributions to biosensor research. Zari played an integral role within the biosensor team, where she helped in developing graphene and microfluidics technology through EPSRC, Innovate UK and Marie Curie sensor projects. The group went on to develop the world's first graphene biosensor, which they are now adapting into platform technology for applications in diagnostics related to dementia, cardiac disease and hepatitis. The projects that Zari worked on led to securing grant income of more than £4 million, 2 granted patents (WO2011004136 and P100072GB) and the publication of more than 70 papers from the group. Zari has a very impressive multi-disciplinary track-record in biosensors development, with a genuine 4* publication in 2D Materials and several other publications, reporting her internationally leading research 3,4 Zari has experience in both the WCPC and CNH research centres and her research resonates strongly with their strategically important activities in graphene, printed batteries and lab on chip technology. Zari's research is also highly industrially relevant to several companies including Biovici, Algipharma, Semefab and Haydale, which is likely to contribute to a REF impact case study. Zari has published more than 20 papers.
1- Tehrani, Z., Korochkina, T., Govindarajan, S., Thomas, D. J., O'Mahony, J., Kettle, J., Claypole, T. C., Gethin, D. T., Ultra-thin flexible screen printed rechargeable polymer battery for wearable electronic applications. Organic Electronics, 2015, 26, p. 386-394.
2- Tehrani, Z., Nordli, H., Chinga-Carrasco, G., Pukstad, B., Gethin, D.T., Translucent and ductile nanocellulose-PEG bionanocomposites—A novel substrate with potential to be functionalized by printing for wound dressing applications. Industrial Crops and Products, 2016. 93, p. 193-202.
3- Tehrani, Z., Burwell, G., Azmi, M. A. M., Castaing, A., Rickman, R., Almarashi, J., Dunstan, P., Beigi, A. M., Doak, S. H., Guy, O. J., Generic epitaxial graphene biosensors for ultrasensitive detection of cancer risk biomarker. 2D Materials, 2014. 1, p.1-19.
4- Azmi, M.A.M., Tehrani, Z., Lewis, R. P., Walker, K. A. D., Jones, D. R., Daniels, D. R., Doak, S. H., Guy, O. J., Highly sensitive covalently functionalised integrated silicon nanowire biosensor devices for detection of cancer risk biomarker. Biosensors & Bioelectronics, 2014. 52, p. 216-224.

Company Profile (Swansea University)

Centre for NanoHealth, Swansea University - The College of Engineering at Swansea University is ranked 10th in the UK in Engineering. With our world-class research, links with industry and outstanding facilities. The £22m Centre for NanoHealth (CNH) at Swansea University is a joint venture between Engineering, Medicine and Science - integrating nanotechnology into medical science applications to provide healthcare solutions to healthcare providers and the healthcare industry.
The centre houses fully integrated nanotechnology clean rooms and biomedical R&D laboratories in a unique facility. The nano-fabrication and characterisation class 1000/100 cleanroom are fully equipped for graphene, silicon and non-silicon, microfluidics (lab on chip) and MEMS processing, whilst the class 1000 bioclean room is used for device functionalisation, and 3D printing. The sensor houses a £1.3m NanoProbe - one of only 5 in the world, as well as new AFM, SEM, XPS, Raman, fluorescence microscopy and other characterisation facilities.
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